RAF Typhoon fighter aircraft have operated alongside French warplanes in a joint strike against an hidden munitions depot in Syria used by the IS group, per a report from the British defence ministry.
The location, identified by intelligence, was believed to be containing munitions and bombs, the statement said, and was located in mountainous terrain just above the ancient city of Palmyra in the heart of Syria.
"Our aircraft utilized Paveway IV guided bombs to strike a several entry passages leading to the depot... preliminary assessments suggest the objective was successfully hit," the ministry announced.
There was no evidence of any civilian impact in the strike late on Saturday and each participating jet returned to base without incident, the MoD added.
The British jets were assisted by a Voyager refuelling tanker.
IS - referred to as the so-called Islamic State - imposed extremist governance over parts of Syria and Iraq before its territorial defeat in 2019.
"This operation shows our UK leadership, and commitment to operate in unison with allied nations, to eliminate any re-emergence of Daesh and their violent and radical beliefs in the area," the British Defence Secretary the minister stated.
UK warplanes have carried out patrols over Syrian airspace to "prevent any efforts to regroup" of Islamic State after its defeat at the Baghuz confrontation in the year 2019, the ministry said.
"I must thank all the members of the UK armed forces who took part in this mission for their professionalism and their courage," the Defence Secretary commented. "They were among thousands of UK service members deployed over the festive period. This operation, to eliminate militants who pose a risk to our security, highlights how UK forces are always on standby, continuously, ensuring Britain's security within its borders and influential overseas."
In December, the US military conducted what it called a "major assault" on Islamic State objectives in Syria, subsequent to an ambush claimed the lives of two US troops and a local interpreter in the Palmyra area.
The United Nations estimates Islamic State still maintains between 5,000 and 7,000 militants in Iraq and Syria.